The main damages of organotin compounds to organisms are: the central nervous system can cause cerebral white matter edema, the process of oxidative phosphorylation in cell energy utilization is hindered, the thymus and lymphatic system Inhibition of cellular immunity, inhibition of hormone secretion, diabetes and hyperlipidemia. Toxicity to humans, local irritation to the skin, respiratory tract, and cornea, systemic poisoning and even death through skin or brain edema. Different types of organotin reagents have varying degrees of toxicity. Long-term low-dose exposure to organotin compounds can cause negative health effects in humans, including damage to the liver and nervous system, as well as reproductive and developmental problems.
For example, tributyltin compound, an organic tin compound, can enter the human body through skin absorption or inhalation of vapor, causing harm to the human nervous system, immune system and reproductive system, and may even cause certain types of cancer. Similarly, organotin oxides, such as hexamethylbis(bisphenoxy)tin, can also cause damage to the human respiratory system, digestive system and muscular system.
Therefore, when using organotin reagents, safety operating procedures should be followed and precautions should be taken. Take care to avoid inhalation, skin contact and ingestion during use. Operation in a well-ventilated environment is required to prevent inhalation of organotin compound vapors and dust. At the same time, corresponding measures should also be taken when disposing of organotin reagent waste to prevent adverse effects on the environment.
