Organotin compounds are a class of organic compounds that contain tin atoms bonded to carbon atoms. These compounds have been widely used as fungicides, fungicides, catalysts, etc. in the past. However, they are considered persistent, bioaccumulative and toxic substances that may be toxic to aquatic organisms and may act as immunotoxins. As a result, major markets around the world have legislated to restrict the use of organotins in finished products. For example, EU REACH Annex XVII Article 20 limits the tin content of dibutyltin (DBT), dioctyltin (DOT) and trisubstituted organotin compounds to 0.1% by weight1.
The main damages of organotin compounds to the human body are: the central nervous system can cause cerebral white matter edema, the process of oxidative phosphorylation in cell energy utilization is hindered, and the thymus and lymphatic system Inhibition, impairment of cellular immunity, and inhibition of hormone secretion cause diabetes and hyperlipidemia.
