[English name] Diphosphorus Pentasulfide&nAnti-aging agentbsp;
【Molecular formula】 P4S10
【Molecular weight】 444.55
[CA registration number] [1314-80-3]
【Structural formula】 P4S10
[Physical Properties] Phosphorus pentasulfide, light yellow crystal. mp 286~290 ℃, d 2.090 g/cm3.
【Notes】 P4S10 is highly flammable and will decompose when exposed to moisture. It should be stored in a sealed container at a low temperature and dry place.
p-Toluenesulfonic Anhydride
P4S10 can act on various types of carbonyl substrates (such as ketones, diketones, esters, amides, etc.) and convert them into the corresponding thiocarbonyl compounds (Formula 1)[1].
Lawesson’s reagent is a commonly used reagent for the synthesis of organosulfur compounds. It can be prepared by reacting P4S10 with anisole (formula 2)[2].
P4S10 is a mild and selective deoxygenating reagent that can reduce sulfoxide compounds to sulfides (Formula 4)[4]. This type of reduction reaction does not affect other functional groups of the substrate such as ester groups, amides and ketones. Interestingly, the sulfone also remains unchanged under the action of P4S10.
P4S10 can also participate in reactions as a dehydrogenation reagent. For example, the aromatization reaction of furan Diels-Alder adducts can be effectively performed under the induction of P4S10 and carbon disulfide (Formula 5) [5].
